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Year : 2019  |  Volume : 35  |  Issue : 2  |  Page : 230-233

Unicentric Castleman disease in the paediatric neck: an unusual case of a rare diagnosis

1 Department of Otolaryngology/Head and Neck Surgery, Freeman Hospital, Newcastle-Upon-Tyne, England
2 Department of Paediatric Immunology, Great North Children’s Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust; Primary Immunodeficiency Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, England

Correspondence Address:
Simon P Leckenby
Department of Otolaryngology, Freeman Hospital, Newcastle-Upon-Tyne, NE7 7DN
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ejo.ejo_105_18

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We present a rare case of unicentric Castleman disease (CD) in the paediatric neck. A 12-year-old Caucasian girl was referred to us due to a slowly enlarging, painless right-sided neck mass. Our thorough investigative approach identified unicentric CD, with previously undocumented CD-like features occurring simultaneously in a separate lesion from the lymph node group involved in unicentric CD. Recognition of CD in the paediatric patient is essential, despite the condition’s rarity, to ensure adequate diagnostic work-up and management. We discuss features of unicentric CD, current concepts surrounding histology of the two separate variants of unicentric and multicentric CD, and the implications for management.

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