The Egyptian Journal of Otolaryngology

ORIGINAL ARTICLE
Year
: 2017  |  Volume : 33  |  Issue : 4  |  Page : 631--636

The effect of direct application of dexamethasone on the round window membrane in patients with sudden sensorineural hearing loss


Fatthi A Abdel Baki1, Ahmed A Omran1, Samir I Asal2, Khaled M Hassan1 
1 Department of Otorhinolaryngology, Faculty of Medicine, University of Alexandria, Alexandria, Egypt
2 Department of Audiovestibular unit, Faculty of Medicine, University of Alexandria, Alexandria, Egypt

Correspondence Address:
Khaled M Hassan
Specialist at Departments of Otorhinolaryngology, Faculty of Medicine, University of Alexandria, Alexandria, 21131
Egypt

Objective The aim of this study was to test the effect of direct application of dexamethasone on the round window (RW) after its adequate exposure following a transcanal approach in patients with sudden sensorineural hearing loss (SSNHL). Study design This investigation was designed to be a prospective cohort study. Patients and methods This study included eighteen adult patients with SSNHL who attended our outpatient clinic at Alexandria Main University Hospital between 1 July 2015 and 1 July 2016. Under general anesthesia the small tympanomeatal flap was elevated to visualize the RW. If it was fully exposed, dexamethasone (4 mg/ml) was applied directly over a piece of gel foam; if not fully exposed the overhang was removed first and then dexamethasone was applied. After 2 weeks, a repeat audiogram was taken in all patients in order to evaluate the efficacy of the treatment on their hearing ability. Results Post-treatment assessment revealed 50% of patients with variable levels of improvement, whereas 50% did not respond to the given treatment. Of the patients showing improvement, 16.7% had normal hearing levels restored. Thus, direct application of dexamethasone on the RW membrane after its adequate exposure may reverse the hearing deficits in a few patients with SSNHL. Conclusion There is a definitive improvement in hearing in patients with SSNHL on direct application of dexamethasone on the RW membrane after its adequate exposure in patients.


How to cite this article:
Abdel Baki FA, Omran AA, Asal SI, Hassan KM. The effect of direct application of dexamethasone on the round window membrane in patients with sudden sensorineural hearing loss.Egypt J Otolaryngol 2017;33:631-636


How to cite this URL:
Abdel Baki FA, Omran AA, Asal SI, Hassan KM. The effect of direct application of dexamethasone on the round window membrane in patients with sudden sensorineural hearing loss. Egypt J Otolaryngol [serial online] 2017 [cited 2024 Mar 29 ];33:631-636
Available from: http://www.ejo.eg.net/article.asp?issn=1012-5574;year=2017;volume=33;issue=4;spage=631;epage=636;aulast=Abdel;type=0